CD4+ T-Lymphocytes Regulate Airway Remodeling and Hyper-Reactivity in a Mouse Model of Chronic Asthma
نویسندگان
چکیده
منابع مشابه
Endothelin-1 directs airway remodeling and hyper-reactivity in a murine asthma model
BACKGROUND The current paradigm describing asthma pathogenesis recognizes the central role of abnormal epithelial function in the generation and maintenance of the disease. However, the mechanisms responsible for the initiation of airway remodeling, which contributes to decreased lung function, remain elusive. Therefore, we aimed to determine the role of altered pulmonary gene expression in dis...
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ژورنال
عنوان ژورنال: Laboratory Investigation
سال: 2002
ISSN: 0023-6837,1530-0307
DOI: 10.1038/labinvest.3780438